Publications

2026

Boumasmoud, Mathilde; León-Sampedro, Ricardo; Beusch, Vera; Benz, Fabienne; Arnoldini, Markus; Hall, Alex R

Interspecies interaction controls Escherichia coli growth in human gut microbiome samples

Proceedings of the National Academy of Sciences

2025

Benz, Fabienne; Beamud, Beatriz; Laurenceau, Raphael; Maire, Amandine; Duportet, Xavier; Decrulle, Antoine; Bikard, David

CRISPR–Cas therapies targeting bacteria

Nature Reviews Bioengineering

Kippnich, Johannes; Benz, Fabienne; Uecker, Hildegard; Baumdicker, Franz

Effectiveness of CRISPR-Cas in sensitizing bacterial populations with plasmid-encoded antimicrobial resistance

Genetics

Enz, Ursina; Gül, Ersin; Maurer, Luca; Čerepenkaitė, Kamilė; Huuskonen, Jemina;  Fattinger, Stefan A; Hardt, Wolf-Dietrich

TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut

PLoS Pathogens

Vaškevičius, Aivaras; Žvirblis, Mantas; Kurtenoka, Maija; Leitans, Janis; Manakova, Elena; Paketurytė-Latvė, Vaida; Kvietkauskaitė, Agnė; Kazaks, Andris; Eimonta, Vladislava; Čerepenkaitė, Kamilė; Kazokaitė-Adomaitienė, Justina; Mickevičiūtė, Aurelija; Juozapaitienė, Vaida; Tars, Kaspars; Gražulis, Saulius; Matulienė, Jurgita; Dudutienė, Virginija; Shubin, Kirill; Matulis, Daumantas; Zubrienė, Asta

Di-meta-Substituted Fluorinated Benzenesulfonamides as Potent and Selective Anticancer Inhibitors of Carbonic Anhydrase IX and XII

Journal of Medicinal Chemistry

2024

Benz, Fabienne; Camara-Wilpert, Sarah; Russel, Jakob; Wandera, Katharina G; Čepaitė, Rimvydė; Ares-Arroyo, Manuel; Gomes-Filho, José Vicente; Englert, Frank; Kuehn, Johannes A; Gloor, Silvana; Mestre, Mario R; Cuénod, Aline; Aguilà-Sans, Mònica; Maccario, Lorrie; Egli, Adrian; Randau, Lennart; Pausch, Patrick; Rocha, Eduardo PC; Beisel, Chase L; Madsen, Jonas S; Bikard, David; Hall, Alex R; Sørensen, Søren J; Pinilla-Redondo, Rafael

Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans

Cell Host & Microbe

Beamud, Beatriz; Benz, Fabienne; Bikard, David

Going viral: The role of mobile genetic elements in bacterial immunity

Cell Host & Microbe

Čepaitė, Rimvydė; Klein, Nathalie; Mikšys, Algirdas; Camara-Wilpert, Sarah; Ragožius, Viktoras; Benz, Fabienne; Skorupskaitė, Aistė; Becker, Hannah; Žvejytė, Gintarė; Steube, Niklas

Structural variation of types IV-A1- and IV-A3-mediated CRISPR interference

Nature Communications

2023

Benz, Fabienne; Hall, Alex R

Host-specific plasmid evolution explains the variable spread of clinical antibiotic-resistance plasmids

Proceedings of the National Academy of Sciences

Bagdonas, Martynas; Čerepenkaitė, Kamilė; Mickevičiūtė, Aurelija; Kananavičiūtė, Rūta; Grybaitė, Birutė; Anusevičius, Kazimieras; Rukšėnaitė, Audronė; Kojis, Tautvydas; Gedgaudas, Marius; Mickevičius, Vytautas; Matulis, Daumantas; Zubrienė, Asta; Matulienė, Jurgita

Screening, synthesis and biochemical characterization of SARS-CoV-2 protease inhibitors

International Journal of Molecular Sciences

2022

Huisman, Jana S; Benz, Fabienne; Duxbury, Sarah JN; de Visser, J Arjan GM; Hall, Alex R; Fischer, Egil AJ; Bonhoeffer, Sebastian

Estimating plasmid conjugation rates: A new computational tool and a critical comparison of methods

Plasmid

2021

Benz, Fabienne; Huisman, Jana S; Bakkeren, Erik; Herter, Joana A; Stadler, Tanja; Ackermann, Martin; Diard, Médéric; Egli, Adrian; Hall, Alex R; Hardt, Wolf-Dietrich

Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo

The ISME journal